Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0317659
PubChem CID
Molecular Formula
C12H7F3N2O
Molecular Weight
252.195 g/mol
Synonyms/Alias
[CHEMBL2046474; 3;4-Difluoro-N-(6-fluoro-3-pyridinyl)benzamide; SCHEMBL14339872; DTXSID401248350; BDBM50420042; 325458-00-2]
InChI Key
BZJXEYDCMWJKHJ-UHFFFAOYSA-N
InChI
InChI=1S/C12H7F3N2O/c13-9-3-1-7(5-10(9)14)12(18)17-8-2-4-11(15)16-6-8/h1-6H,(H,17,18)
IUPAC Name
3,4-difluoro-N-(6-fluoropyridin-3-yl)benzamide
CAS Number
325458-00-2

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

25 26 0 0 0 0 0 0 0 0999 V2000
-2.3718 1.8398 0.2658 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.7596 1.8229 0.0976 C 0 0 0 0 0 0 0 0 0 0 0 0
-4.4135 0.629...

Experimental Data

Activity Data

Target Ion Channel
Potassium voltage-gated channel subfamily KQT member 2/3
Uniprot Accession Number
Function
Agonist
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
EC50: 4800 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
Not mention
Holding Potential
Not specified
Temperature
Not mention
Test Method
Efflux Assay ([86] Rubidium Ion)
Test Species
CHO cell (Chinese Hamster Ovary cell)

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
18
Rotatable Bonds
2
logP
2.7512
Complexity
58.5062
TPSA (Ų)
41.99
H-Bond Donors
1
H-Bond Acceptors
2
Ring Count
2
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